Role of Proprotein Convertase Subtilisin/Kexin Type 9 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts
BackgroundThe proprotein convertase subtilisin/kexin type 9 (PCSK9) has been implicated in the pathogenesis of inflammatory diseases. We sought to investigate the role of PCSK9 in the pathogenesis of Graves’ orbitopathy (GO) and whether it may be a legitimate target for treatment.MethodsThe PCSK9 wa...
Main Authors: | Ga Eun Lee, Jinjoo Kim, Jihei Sara Lee, JaeSang Ko, Eun Jig Lee, Jin Sook Yoon |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-01-01
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Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2020.607144/full |
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