Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection
Extracellular vesicles have been implicated in the transmission of pathogens from the arthropod to the human host. Here the authors show that tick-derived extracellular vesicles play a role in feeding and modulate the outcome of bacterial infection.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2021-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-23900-8 |
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doaj-41e1c07d29b74e5f972379e9fa87802a2021-06-20T11:12:28ZengNature Publishing GroupNature Communications2041-17232021-06-0112111710.1038/s41467-021-23900-8Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infectionAdela S. Oliva Chávez0Xiaowei Wang1Liron Marnin2Nathan K. Archer3Holly L. Hammond4Erin E. McClure Carroll5Dana K. Shaw6Brenden G. Tully7Amanda D. Buskirk8Shelby L. Ford9L. Rainer Butler10Preeti Shahi11Kateryna Morozova12Cristina C. Clement13Lauren Lawres14Anya J. O’ Neal15Choukri Ben Mamoun16Kathleen L. Mason17Brandi E. Hobbs18Glen A. Scoles19Eileen M. Barry20Daniel E. Sonenshine21Utpal Pal22Jesus G. Valenzuela23Marcelo B. Sztein24Marcela F. Pasetti25Michael L. Levin26Michail Kotsyfakis27Steven M. Jay28Jason F. Huntley29Lloyd S. Miller30Laura Santambrogio31Joao H. F. Pedra32Department of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Dermatology, Johns Hopkins University School of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life SciencesCenter for Vaccine Development and Global Health, University of Maryland School of MedicineCenters for Disease Control and PreventionDepartment of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineDepartment of Pathology, Albert Einstein College of MedicineDepartment of Pathology, Albert Einstein College of MedicineSection of Infectious Diseases, Department of Internal Medicine, Yale University School of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineSection of Infectious Diseases, Department of Internal Medicine, Yale University School of MedicineUSDA, ARS, Animal Disease Research Unit, Washington State UniversityDepartment of Microbiology and Immunology, University of Maryland School of MedicineUSDA, ARS, Animal Disease Research Unit, Washington State UniversityCenter for Vaccine Development and Global Health, University of Maryland School of MedicineVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of HealthDepartment of Veterinary Medicine, University of MarylandVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of HealthCenter for Vaccine Development and Global Health, University of Maryland School of MedicineCenter for Vaccine Development and Global Health, University of Maryland School of MedicineCenters for Disease Control and PreventionInstitute of Parasitology, Biology Center of the Czech Academy of SciencesFischell Department of Bioengineering, University of MarylandDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life SciencesDepartment of Dermatology, Johns Hopkins University School of MedicineDepartment of Microbiology and Immunology, Albert Einstein College of MedicineDepartment of Microbiology and Immunology, University of Maryland School of MedicineExtracellular vesicles have been implicated in the transmission of pathogens from the arthropod to the human host. Here the authors show that tick-derived extracellular vesicles play a role in feeding and modulate the outcome of bacterial infection.https://doi.org/10.1038/s41467-021-23900-8 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Adela S. Oliva Chávez Xiaowei Wang Liron Marnin Nathan K. Archer Holly L. Hammond Erin E. McClure Carroll Dana K. Shaw Brenden G. Tully Amanda D. Buskirk Shelby L. Ford L. Rainer Butler Preeti Shahi Kateryna Morozova Cristina C. Clement Lauren Lawres Anya J. O’ Neal Choukri Ben Mamoun Kathleen L. Mason Brandi E. Hobbs Glen A. Scoles Eileen M. Barry Daniel E. Sonenshine Utpal Pal Jesus G. Valenzuela Marcelo B. Sztein Marcela F. Pasetti Michael L. Levin Michail Kotsyfakis Steven M. Jay Jason F. Huntley Lloyd S. Miller Laura Santambrogio Joao H. F. Pedra |
| spellingShingle |
Adela S. Oliva Chávez Xiaowei Wang Liron Marnin Nathan K. Archer Holly L. Hammond Erin E. McClure Carroll Dana K. Shaw Brenden G. Tully Amanda D. Buskirk Shelby L. Ford L. Rainer Butler Preeti Shahi Kateryna Morozova Cristina C. Clement Lauren Lawres Anya J. O’ Neal Choukri Ben Mamoun Kathleen L. Mason Brandi E. Hobbs Glen A. Scoles Eileen M. Barry Daniel E. Sonenshine Utpal Pal Jesus G. Valenzuela Marcelo B. Sztein Marcela F. Pasetti Michael L. Levin Michail Kotsyfakis Steven M. Jay Jason F. Huntley Lloyd S. Miller Laura Santambrogio Joao H. F. Pedra Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Nature Communications |
| author_facet |
Adela S. Oliva Chávez Xiaowei Wang Liron Marnin Nathan K. Archer Holly L. Hammond Erin E. McClure Carroll Dana K. Shaw Brenden G. Tully Amanda D. Buskirk Shelby L. Ford L. Rainer Butler Preeti Shahi Kateryna Morozova Cristina C. Clement Lauren Lawres Anya J. O’ Neal Choukri Ben Mamoun Kathleen L. Mason Brandi E. Hobbs Glen A. Scoles Eileen M. Barry Daniel E. Sonenshine Utpal Pal Jesus G. Valenzuela Marcelo B. Sztein Marcela F. Pasetti Michael L. Levin Michail Kotsyfakis Steven M. Jay Jason F. Huntley Lloyd S. Miller Laura Santambrogio Joao H. F. Pedra |
| author_sort |
Adela S. Oliva Chávez |
| title |
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection |
| title_short |
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection |
| title_full |
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection |
| title_fullStr |
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection |
| title_full_unstemmed |
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection |
| title_sort |
tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2021-06-01 |
| description |
Extracellular vesicles have been implicated in the transmission of pathogens from the arthropod to the human host. Here the authors show that tick-derived extracellular vesicles play a role in feeding and modulate the outcome of bacterial infection. |
| url |
https://doi.org/10.1038/s41467-021-23900-8 |
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