Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum

Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum

Lipid droplets (LDs) and peroxisomes both emerge from the endoplasmic reticulum (ER). Here, the authors show that yeast Seipin and Pex30 proteins act together to regulate budding of these organelles from the same subdomain of the ER.

Bibliographic Details
Main Authors: Sihui Wang, Fatima-Zahra Idrissi, Martin Hermansson, Alexandra Grippa, Christer S. Ejsing, Pedro Carvalho
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05278-2
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spelling doaj-41f77d38f6a44557a6cd2e203937e85f2021-05-11T10:04:15ZengNature Publishing GroupNature Communications2041-17232018-07-019111210.1038/s41467-018-05278-2Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulumSihui Wang0Fatima-Zahra Idrissi1Martin Hermansson2Alexandra Grippa3Christer S. Ejsing4Pedro Carvalho5Sir William Dunn School of Pathology, University of OxfordCell and Developmental Biology Programme, Centre for Genomic Regulation (CRG)Department of Biochemistry and Molecular Biology, Villum Center for Bioanalytical Sciences, University of Southern DenmarkCell and Developmental Biology Programme, Centre for Genomic Regulation (CRG)Department of Biochemistry and Molecular Biology, Villum Center for Bioanalytical Sciences, University of Southern DenmarkSir William Dunn School of Pathology, University of OxfordLipid droplets (LDs) and peroxisomes both emerge from the endoplasmic reticulum (ER). Here, the authors show that yeast Seipin and Pex30 proteins act together to regulate budding of these organelles from the same subdomain of the ER.https://doi.org/10.1038/s41467-018-05278-2
collection DOAJ
language English
format Article
sources DOAJ
author Sihui Wang
Fatima-Zahra Idrissi
Martin Hermansson
Alexandra Grippa
Christer S. Ejsing
Pedro Carvalho
spellingShingle Sihui Wang
Fatima-Zahra Idrissi
Martin Hermansson
Alexandra Grippa
Christer S. Ejsing
Pedro Carvalho
Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
Nature Communications
author_facet Sihui Wang
Fatima-Zahra Idrissi
Martin Hermansson
Alexandra Grippa
Christer S. Ejsing
Pedro Carvalho
author_sort Sihui Wang
title Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
title_short Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
title_full Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
title_fullStr Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
title_full_unstemmed Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
title_sort seipin and the membrane-shaping protein pex30 cooperate in organelle budding from the endoplasmic reticulum
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-07-01
description Lipid droplets (LDs) and peroxisomes both emerge from the endoplasmic reticulum (ER). Here, the authors show that yeast Seipin and Pex30 proteins act together to regulate budding of these organelles from the same subdomain of the ER.
url https://doi.org/10.1038/s41467-018-05278-2
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AT fatimazahraidrissi seipinandthemembraneshapingproteinpex30cooperateinorganellebuddingfromtheendoplasmicreticulum
AT martinhermansson seipinandthemembraneshapingproteinpex30cooperateinorganellebuddingfromtheendoplasmicreticulum
AT alexandragrippa seipinandthemembraneshapingproteinpex30cooperateinorganellebuddingfromtheendoplasmicreticulum
AT christersejsing seipinandthemembraneshapingproteinpex30cooperateinorganellebuddingfromtheendoplasmicreticulum
AT pedrocarvalho seipinandthemembraneshapingproteinpex30cooperateinorganellebuddingfromtheendoplasmicreticulum
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