The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review
In comparison with other animal venoms, fish venoms remain relatively understudied. This is especially true for that of the lesser Echiichthys vipera and greater weever fish Trachinus draco which, apart from the isolation of their unique venom cytolysins, trachinine and dracotoxin, respectively, rem...
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doaj-41fea4965cab489b9eab5dab083e39882020-11-25T03:24:05ZengElsevierToxicon: X2590-17102020-06-016The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A reviewLucy M. Gorman0Sarah J. Judge1Myriam Fezai2Mohamed Jemaà3John B. Harris4Gary S. Caldwell5School of Natural and Environmental Sciences, Newcastle University, Ridley Building, Claremont Road, Newcastle Upon Tyne, NE1 7RU, UK; Corresponding author.Medical Toxicology Centre, Newcastle University, Wolfson Building, Claremont Place, Newcastle Upon Tyne, NE2 4AA, UKDepartment of Physiology I, University of Tübingen, Tübingen, GermanyDepartment of Laboratory Medicine, Translational Cancer Research, Lund University, Lund, SwedenMedical Toxicology Centre and Institute of Neuroscience, Newcastle University, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UKSchool of Natural and Environmental Sciences, Newcastle University, Ridley Building, Claremont Road, Newcastle Upon Tyne, NE1 7RU, UKIn comparison with other animal venoms, fish venoms remain relatively understudied. This is especially true for that of the lesser Echiichthys vipera and greater weever fish Trachinus draco which, apart from the isolation of their unique venom cytolysins, trachinine and dracotoxin, respectively, remain relatively uncharacterised. Envenomation reports mainly include mild symptoms consisting of nociception and inflammation. However, like most fish venoms, if the venom becomes systemic it causes cardiorespiratory and blood pressure changes. Although T. draco venom has not been studied since the 1990's, recent studies on E. vipera venom have discovered novel cytotoxic components on human cancer cells, but due to the scarcity of research on the molecular make-up of the venom, the molecule(s) causing this cytotoxicity remains unknown. This review analyses past studies on E. vipera and T. draco venom, the methods used in the , the venom constituents characterised, the reported symptoms of envenomation and compares these findings with those from other venomous Scorpaeniformes.http://www.sciencedirect.com/science/article/pii/S2590171020300035Echiichthys viperaTrachinus dracoTrachinineDracotoxinWeever fish venomCytolytic |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lucy M. Gorman Sarah J. Judge Myriam Fezai Mohamed Jemaà John B. Harris Gary S. Caldwell |
spellingShingle |
Lucy M. Gorman Sarah J. Judge Myriam Fezai Mohamed Jemaà John B. Harris Gary S. Caldwell The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review Toxicon: X Echiichthys vipera Trachinus draco Trachinine Dracotoxin Weever fish venom Cytolytic |
author_facet |
Lucy M. Gorman Sarah J. Judge Myriam Fezai Mohamed Jemaà John B. Harris Gary S. Caldwell |
author_sort |
Lucy M. Gorman |
title |
The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review |
title_short |
The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review |
title_full |
The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review |
title_fullStr |
The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review |
title_full_unstemmed |
The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review |
title_sort |
venoms of the lesser (echiichthys vipera) and greater (trachinus draco) weever fish– a review |
publisher |
Elsevier |
series |
Toxicon: X |
issn |
2590-1710 |
publishDate |
2020-06-01 |
description |
In comparison with other animal venoms, fish venoms remain relatively understudied. This is especially true for that of the lesser Echiichthys vipera and greater weever fish Trachinus draco which, apart from the isolation of their unique venom cytolysins, trachinine and dracotoxin, respectively, remain relatively uncharacterised. Envenomation reports mainly include mild symptoms consisting of nociception and inflammation. However, like most fish venoms, if the venom becomes systemic it causes cardiorespiratory and blood pressure changes. Although T. draco venom has not been studied since the 1990's, recent studies on E. vipera venom have discovered novel cytotoxic components on human cancer cells, but due to the scarcity of research on the molecular make-up of the venom, the molecule(s) causing this cytotoxicity remains unknown. This review analyses past studies on E. vipera and T. draco venom, the methods used in the , the venom constituents characterised, the reported symptoms of envenomation and compares these findings with those from other venomous Scorpaeniformes. |
topic |
Echiichthys vipera Trachinus draco Trachinine Dracotoxin Weever fish venom Cytolytic |
url |
http://www.sciencedirect.com/science/article/pii/S2590171020300035 |
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