Inhibition of Ceramide De Novo Synthesis Affects Adipocytokine Secretion and Improves Systemic and Adipose Tissue Insulin Sensitivity

Inhibition of Ceramide De Novo Synthesis Affects Adipocytokine Secretion and Improves Systemic and Adipose Tissue Insulin Sensitivity

Ceramide accumulation in muscle and in liver is implicated in the induction of insulin resistance. Much less in known about the role of ceramide in adipose tissue. The aim of the present study was to elucidate the role of ceramide in adipose tissue and to clarify whether lipids participate in the re...

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Bibliographic Details
Main Authors:	Agnieszka U. Blachnio-Zabielska, Hady Razak Hady, Adam R. Markowski, Adam Kurianiuk, Alicja Karwowska, Jan Górski, Piotr Zabielski
Format:	Article
Language:	English
Published:	MDPI AG 2018-12-01
Series:	International Journal of Molecular Sciences
Subjects:	ceramide insulin resistance visceral adipose tissue subcutaneous adipose tissue metabolic disorders mass spectrometry
Online Access:	https://www.mdpi.com/1422-0067/19/12/3995

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