HeurAA: accurate and fast detection of genetic variations with a novel heuristic amplicon aligner program for next generation sequencing.
Next generation sequencing (NGS) of PCR amplicons is a standard approach to detect genetic variations in personalized medicine such as cancer diagnostics. Computer programs used in the NGS community often miss insertions and deletions (indels) that constitute a large part of known human mutations. W...
Main Authors: | Lőrinc S Pongor, Ferenc Pintér, István Peták |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23349847/?tool=EBI |
Similar Items
-
Fast and sensitive alignment of microbial whole genome sequencing reads to large sequence datasets on a desktop PC: application to metagenomic datasets and pathogen identification.
by: Lőrinc S Pongor, et al.
Published: (2014-01-01) -
BAMClipper: removing primers from alignments to minimize false-negative mutations in amplicon next-generation sequencing
by: Chun Hang Au, et al.
Published: (2017-05-01) -
A fast and accurate aligner for detecting non-templated tailing in small silencing RNAs by next generation sequencing
by: Chou, Min-Te, et al.
Published: (2015) -
Kalign – an accurate and fast multiple sequence alignment algorithm
by: Sonnhammer Erik LL, et al.
Published: (2005-12-01) -
Development of Fast and Accurate Genomic Sequence Alignment Methods
by: Nakato, Ryuichiro
Published: (2010)