Advances in the study of macrophages in wound healing
Macrophages are a group of immune cells with highly heterogeneous phenotypes and functions, which run through the whole process of tissue repair. Macrophages are distributed in various organs and tissues of the body, which are a kind of cell population with plasticity and high heterogeneity in th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Board of Journal of Hainan Medical University
2019-08-01
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| Series: | Journal of Hainan Medical University |
| Subjects: | |
| Online Access: | http://www.hnykdxxb.com/PDF/201915/16.pdf |
| Summary: | Macrophages are a group of immune cells with highly heterogeneous phenotypes and
functions, which run through the whole process of tissue repair. Macrophages are distributed
in various organs and tissues of the body, which are a kind of cell population with plasticity
and high heterogeneity in the functional state. Under various conditions, it can be transformed
into M1-type (classically activated macrophage) and M2-type macrophages (alternatively
activated macrophage).It was also found that the phenotypic polarization of macrophages
was regulated by a variety of conditions. This review summarizes the existing studies on the
effect of macrophage subtypes on wound repair and the mechanism of regulating macrophage
phenotype polarization, so as to provide theoretical basis for further studies. |
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| ISSN: | 1007-1237 1007-1237 |