Advances in the study of macrophages in wound healing
Macrophages are a group of immune cells with highly heterogeneous phenotypes and functions, which run through the whole process of tissue repair. Macrophages are distributed in various organs and tissues of the body, which are a kind of cell population with plasticity and high heterogeneity in th...
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doaj-42789b3baefd4376b622d39e98fdaa072020-11-25T01:51:47ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372019-08-0125156669Advances in the study of macrophages in wound healingYu-Lian Yin0Pan Ling-Ting1 Yi-Qin Cheng2Hong-Feng Chen3Department of Breast Disease,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,ChinaDepartment of Breast Disease,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,ChinaDepartment of Breast Disease,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,ChinaDepartment of Breast Disease,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,ChinaMacrophages are a group of immune cells with highly heterogeneous phenotypes and functions, which run through the whole process of tissue repair. Macrophages are distributed in various organs and tissues of the body, which are a kind of cell population with plasticity and high heterogeneity in the functional state. Under various conditions, it can be transformed into M1-type (classically activated macrophage) and M2-type macrophages (alternatively activated macrophage).It was also found that the phenotypic polarization of macrophages was regulated by a variety of conditions. This review summarizes the existing studies on the effect of macrophage subtypes on wound repair and the mechanism of regulating macrophage phenotype polarization, so as to provide theoretical basis for further studies.http://www.hnykdxxb.com/PDF/201915/16.pdfmacrophagephenotypic transformationregulatory mechanism |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yu-Lian Yin Pan Ling-Ting Yi-Qin Cheng Hong-Feng Chen |
spellingShingle |
Yu-Lian Yin Pan Ling-Ting Yi-Qin Cheng Hong-Feng Chen Advances in the study of macrophages in wound healing Journal of Hainan Medical University macrophage phenotypic transformation regulatory mechanism |
author_facet |
Yu-Lian Yin Pan Ling-Ting Yi-Qin Cheng Hong-Feng Chen |
author_sort |
Yu-Lian Yin |
title |
Advances in the study of macrophages in wound healing |
title_short |
Advances in the study of macrophages in wound healing |
title_full |
Advances in the study of macrophages in wound healing |
title_fullStr |
Advances in the study of macrophages in wound healing |
title_full_unstemmed |
Advances in the study of macrophages in wound healing |
title_sort |
advances in the study of macrophages in wound healing |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2019-08-01 |
description |
Macrophages are a group of immune cells with highly heterogeneous phenotypes and
functions, which run through the whole process of tissue repair. Macrophages are distributed
in various organs and tissues of the body, which are a kind of cell population with plasticity
and high heterogeneity in the functional state. Under various conditions, it can be transformed
into M1-type (classically activated macrophage) and M2-type macrophages (alternatively
activated macrophage).It was also found that the phenotypic polarization of macrophages
was regulated by a variety of conditions. This review summarizes the existing studies on the
effect of macrophage subtypes on wound repair and the mechanism of regulating macrophage
phenotype polarization, so as to provide theoretical basis for further studies. |
topic |
macrophage phenotypic transformation regulatory mechanism |
url |
http://www.hnykdxxb.com/PDF/201915/16.pdf |
work_keys_str_mv |
AT yulianyin advancesinthestudyofmacrophagesinwoundhealing AT panlingting advancesinthestudyofmacrophagesinwoundhealing AT yiqincheng advancesinthestudyofmacrophagesinwoundhealing AT hongfengchen advancesinthestudyofmacrophagesinwoundhealing |
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1724996347839381504 |