Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice.
The curry spice curcumin plays a protective role in mouse models of neurodegenerative diseases, and can also directly modulate aggregation of α-synuclein protein in vitro, yet no studies have described the interaction of curcumin and α-synuclein in genetic synucleinopathy mouse models. Here we exami...
Main Authors: | Kateri J Spinelli, Valerie R Osterberg, Charles K Meshul, Amala Soumyanath, Vivek K Unni |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4452784?pdf=render |
Similar Items
-
Proteasome dysfunction in aged human α-synuclein transgenic mice
by: Li Chen, et al.
Published: (2006-07-01) -
Modelling Parkinson's disease with α-synuclein transgenic mice
by: Scudamore, Owen
Published: (2013) -
Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism
by: Valerie R. Osterberg, et al.
Published: (2015-03-01) -
7,8-Dihydroxyflavone ameliorates mitochondrial impairment and motor dysfunction in the α-synuclein 1–103 transgenic mice
by: Bu, L., et al.
Published: (2022) -
Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils
by: Jess-Karan S. Dhillon, et al.
Published: (2019-05-01)