The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
<p><strong>Purpose:</strong> To compare the results of laser treatment and intravitreal ranibizumab injections in patients with DME consistent with the level of VEGF A in tear fluid.</p><p><br /><strong>Methods:</strong> The progress of visual acuity,...
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doaj-4294dec9787048189c65aea32997455f2020-11-24T22:40:53ZrusOphthalmology Publishing GroupOftalʹmologiâ 1816-50952014-07-01102444977The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2I. V. Vorobieva0E. V. Parfenova1D. A. Merkushenkova2P. I. Makarevich3V. I. Alekhnovich4ГБОУ ДПО РМАПО Минздрава РоссииГБОУ ДПО РМАПО Минздрава РоссииФГБОУ ВПО МГУ им. М. В. ЛомоносоваФГБОУ ВПО МГУ им. М. В. ЛомоносоваФГБОУ ВПО МГТУ им. Н. Э. Баумана<p><strong>Purpose:</strong> To compare the results of laser treatment and intravitreal ranibizumab injections in patients with DME consistent with the level of VEGF A in tear fluid.</p><p><br /><strong>Methods:</strong> The progress of visual acuity, retinal thickness and light sensivity after laser treatment and ranibizumab intravitreal injection has been assessed.</p><p><br /><strong>Results:</strong> One month after the treatment the main effect of laser was the decrease of retinal thickness, whereas after ranibizumab — the increase of visual acuity. The significant decrease of VEGF A level in tear fluid was found only in ranibizumab group.</p><p><br /><strong>Conclusion:</strong> Laser treatment of DME leads to permanent retinal thickness decrease and insignificant functional improvement in comparison with ranibizumab IV injection, which leads to temporary morphological and functional improvement.</p>http://www.ophthalmojournal.com/index.php/opht/article/view/77DMEantiangiogenic treatmentVEGF Alaserranibizumab |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
I. V. Vorobieva E. V. Parfenova D. A. Merkushenkova P. I. Makarevich V. I. Alekhnovich |
spellingShingle |
I. V. Vorobieva E. V. Parfenova D. A. Merkushenkova P. I. Makarevich V. I. Alekhnovich The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2 Oftalʹmologiâ DME antiangiogenic treatment VEGF A laser ranibizumab |
author_facet |
I. V. Vorobieva E. V. Parfenova D. A. Merkushenkova P. I. Makarevich V. I. Alekhnovich |
author_sort |
I. V. Vorobieva |
title |
The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2 |
title_short |
The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2 |
title_full |
The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2 |
title_fullStr |
The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2 |
title_full_unstemmed |
The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2 |
title_sort |
results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2 |
publisher |
Ophthalmology Publishing Group |
series |
Oftalʹmologiâ |
issn |
1816-5095 |
publishDate |
2014-07-01 |
description |
<p><strong>Purpose:</strong> To compare the results of laser treatment and intravitreal ranibizumab injections in patients with DME consistent with the level of VEGF A in tear fluid.</p><p><br /><strong>Methods:</strong> The progress of visual acuity, retinal thickness and light sensivity after laser treatment and ranibizumab intravitreal injection has been assessed.</p><p><br /><strong>Results:</strong> One month after the treatment the main effect of laser was the decrease of retinal thickness, whereas after ranibizumab — the increase of visual acuity. The significant decrease of VEGF A level in tear fluid was found only in ranibizumab group.</p><p><br /><strong>Conclusion:</strong> Laser treatment of DME leads to permanent retinal thickness decrease and insignificant functional improvement in comparison with ranibizumab IV injection, which leads to temporary morphological and functional improvement.</p> |
topic |
DME antiangiogenic treatment VEGF A laser ranibizumab |
url |
http://www.ophthalmojournal.com/index.php/opht/article/view/77 |
work_keys_str_mv |
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