Answering the Call: Coping with DNA Damage at the Most Inopportune Time

DNA damage incurred during the process of chromosomal replication has a particularly high possibility of resulting in mutagenesis or lethality for the cell. The SOS response of Escherichia coli appears to be well adapted for this particular situation and involves the coordinated up-regulation of gen...

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Bibliographic Details
Main Authors: David J. Crowley, Justin Courcelle
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/S1110724302202016

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