Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis
<p>Abstract</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus that shows a restricted in vivo tropism for subsets of porcine macrophages, with alveolar macrophages being major target cells. The virus is associated with respiratory problems in pigs...
Main Authors: | De Baere Miet I, Van Gorp Hanne, Delputte Peter L, Nauwynck Hans J |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-05-01
|
Series: | Veterinary Research |
Online Access: | http://www.veterinaryresearch.org/content/43/1/47 |
Similar Items
-
Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages.
by: Peter L Delputte, et al.
Published: (2011-01-01) -
Analysis of the Binding Sites of Porcine Sialoadhesin Receptor with PRRSV
by: Yibo Jiang, et al.
Published: (2013-12-01) -
Susceptible cell lines for the production of porcine reproductive and respiratory syndrome virus by stable transfection of sialoadhesin and CD163
by: Delrue Iris, et al.
Published: (2010-06-01) -
The characterisation and functional analysis of sialoadhesin (siglec-1) and novel siglecs expressed on mononuclear phagocytes
by: Munday, James
Published: (1999) -
Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169.
by: Weihsu C Chen, et al.
Published: (2012-01-01)