Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8<sup>+</sup> T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery System

The ability of vaccines to induce T cell responses is crucial for preventing diseases caused by viruses. Nanoparticles (NPs) are considered to be efficient tools for the initiation of potent immune responses. Calcium phosphate (CaP) NPs are a class of biodegradable nanocarriers that are able to deli...

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Bibliographic Details
Main Authors: Florian Scheffel, Torben Knuschke, Lucas Otto, Sebastian Kollenda, Viktoriya Sokolova, Christine Cosmovici, Jan Buer, Jörg Timm, Matthias Epple, Astrid M. Westendorf
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/1/110