High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan
Background: Developmental disorders and high Helicobacter pylori (H. pylori) infection rates have been reported. This study aimed to examine the prevalence of H. pylori in a special needs school where all students had developmental disorders in Japan.Methods: In 2017, third-grade junior high school...
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Frontiers Media S.A.
2021-07-01
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Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2021.697200/full |
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doaj-42ef955e699e4cb989c5deba93c219312021-07-08T04:39:50ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602021-07-01910.3389/fped.2021.697200697200High Prevalence of Helicobacter pylori Infection in Special Needs Schools in JapanToshihiko Kakiuchi0Ayako Takamori1Muneaki Matsuo2Department of Pediatrics, Faculty of Medicine, Saga University, Saga, JapanClinical Research Center, Saga University Hospital, Saga, JapanDepartment of Pediatrics, Faculty of Medicine, Saga University, Saga, JapanBackground: Developmental disorders and high Helicobacter pylori (H. pylori) infection rates have been reported. This study aimed to examine the prevalence of H. pylori in a special needs school where all students had developmental disorders in Japan.Methods: In 2017, third-grade junior high school and second- and third-grade high school students attending a special needs school with developmental disorders were enrolled. Participants of Saga Prefecture's H. pylori test and treat project, which comprised third-grade junior high school students not from special needs school, were assigned to the control group.Results: In the control group, H. pylori positive results were 3.18% (228/7,164) students. Similarly, in developmental disorder group, H. pylori positive results were 6.80% (13/191) students. For the developmental disorder and control groups, this present examination sensitivity was 7.03% (13/185), specificity was 96.76% (6,815/7,043), positive predictive value was 5.39% (13/241), negative predictive value was 97.54% (6,815/6,987), Likelihood ratio of a positive result 2.17 and Odds ratio was 2.26 (95% confidence interval: 1.27–4.03, p = 0.005).Conclusion: The prevalence of H. pylori infection was significantly higher in adolescents with developmental disorders than in typically developing adolescents.https://www.frontiersin.org/articles/10.3389/fped.2021.697200/fullHelicobacter pyloridevelopmental disordersadolescentsspecial needs schoolsJapan |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Toshihiko Kakiuchi Ayako Takamori Muneaki Matsuo |
spellingShingle |
Toshihiko Kakiuchi Ayako Takamori Muneaki Matsuo High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan Frontiers in Pediatrics Helicobacter pylori developmental disorders adolescents special needs schools Japan |
author_facet |
Toshihiko Kakiuchi Ayako Takamori Muneaki Matsuo |
author_sort |
Toshihiko Kakiuchi |
title |
High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan |
title_short |
High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan |
title_full |
High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan |
title_fullStr |
High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan |
title_full_unstemmed |
High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan |
title_sort |
high prevalence of helicobacter pylori infection in special needs schools in japan |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Pediatrics |
issn |
2296-2360 |
publishDate |
2021-07-01 |
description |
Background: Developmental disorders and high Helicobacter pylori (H. pylori) infection rates have been reported. This study aimed to examine the prevalence of H. pylori in a special needs school where all students had developmental disorders in Japan.Methods: In 2017, third-grade junior high school and second- and third-grade high school students attending a special needs school with developmental disorders were enrolled. Participants of Saga Prefecture's H. pylori test and treat project, which comprised third-grade junior high school students not from special needs school, were assigned to the control group.Results: In the control group, H. pylori positive results were 3.18% (228/7,164) students. Similarly, in developmental disorder group, H. pylori positive results were 6.80% (13/191) students. For the developmental disorder and control groups, this present examination sensitivity was 7.03% (13/185), specificity was 96.76% (6,815/7,043), positive predictive value was 5.39% (13/241), negative predictive value was 97.54% (6,815/6,987), Likelihood ratio of a positive result 2.17 and Odds ratio was 2.26 (95% confidence interval: 1.27–4.03, p = 0.005).Conclusion: The prevalence of H. pylori infection was significantly higher in adolescents with developmental disorders than in typically developing adolescents. |
topic |
Helicobacter pylori developmental disorders adolescents special needs schools Japan |
url |
https://www.frontiersin.org/articles/10.3389/fped.2021.697200/full |
work_keys_str_mv |
AT toshihikokakiuchi highprevalenceofhelicobacterpyloriinfectioninspecialneedsschoolsinjapan AT ayakotakamori highprevalenceofhelicobacterpyloriinfectioninspecialneedsschoolsinjapan AT muneakimatsuo highprevalenceofhelicobacterpyloriinfectioninspecialneedsschoolsinjapan |
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