Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS.

Despite the advent of highly active anti-retroviral therapy (HAART), HIV-associated neurocognitive disorders continue to be a significant problem. In efforts to understand and alleviate neurocognitive deficits associated with HIV, we used an accelerated simian immunodeficiency virus (SIV) macaque mo...

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Main Authors: Eva-Maria Ratai, Jeffrey P Bombardier, Chan-Gyu Joo, Lakshmanan Annamalai, Tricia H Burdo, Jennifer Campbell, Robert Fell, Reza Hakimelahi, Julian He, Patrick Autissier, Margaret R Lentz, Elkan F Halpern, Eliezer Masliah, Kenneth C Williams, Susan V Westmoreland, R Gilberto González
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2866543?pdf=render