DLA class II risk haplotypes for autoimmune diseases in the bearded collie offer insight to autoimmunity signatures across dog breeds

DLA class II risk haplotypes for autoimmune diseases in the bearded collie offer insight to autoimmunity signatures across dog breeds

Abstract Background Primary hypoadrenocorticism (Addison’s disease, AD) and symmetrical lupoid onychodystrophy (SLO) are two clinical conditions with an autoimmune etiology that occur in multiple dog breeds. In man, autoimmunity is associated with polymorphisms in immune-related genes that result in...

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Bibliographic Details
Main Authors: Liza C. Gershony, Janelle M. Belanger, Andrea D. Short, Myly Le, Marjo K. Hytönen, Hannes Lohi, Thomas R. Famula, Lorna J. Kennedy, Anita M. Oberbauer
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Canine Genetics and Epidemiology
Subjects:
(3–10): Dog
Autoimmune
MHC
DLA
Addison’s disease
SLO
Online Access:http://link.springer.com/article/10.1186/s40575-019-0070-7

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