Role of hypothalamic-pituitary adrenal-axis, toll-like receptors, and macrophage polarization in pre-atherosclerotic changes induced by social isolation stress in mice

Abstract It has been well documented that chronic stress can induce atherosclerotic changes, however, the underlying mechanisms is yet to be established. In this regard, this study aimed to elucidate the relation between hypothalamic-pituitary adrenal-axis (HPA-axis), toll-like receptors (TLRs), as...

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Bibliographic Details
Main Authors: Arvin Haj-Mirzaian, Kiana Ramezanzadeh, Siavash Shariatzadeh, Michael Tajik, Farima Khalafi, Armin Tafazolimoghadam, Mahla Radmard, Alireza Rahbar, Fardad Pirri, Kiarash Kazemi, Ayda Khosravi, Niloufar Shababi, Ahmad Reza Dehpour
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98276-2

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