A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial
Fatty acid (FA) chemoreception in the oral cavity, known as fat taste, may trigger a satiety response that is homologous to FA chemoreception in the gastrointestinal tract. In addition, individuals with an impaired fat taste sensitivity are more likely to have an impaired satiety response. This stud...
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doaj-4342ad8c6ed64fd0a6c17b75a9f6313f2020-11-25T02:28:13ZengMDPI AGNutrients2072-66432020-03-0112367810.3390/nu12030678nu12030678A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over TrialAndrew Costanzo0Catherine G Russell1Simone Lewin2Russell Keast3CASS Food Research Centre, School of Exercise and Nutrition Sciences Deakin University, 1 Gheringhap St, 3220 Geelong, VIC, AustraliaCASS Food Research Centre, School of Exercise and Nutrition Sciences Deakin University, 1 Gheringhap St, 3220 Geelong, VIC, AustraliaCASS Food Research Centre, School of Exercise and Nutrition Sciences Deakin University, 1 Gheringhap St, 3220 Geelong, VIC, AustraliaCASS Food Research Centre, School of Exercise and Nutrition Sciences Deakin University, 1 Gheringhap St, 3220 Geelong, VIC, AustraliaFatty acid (FA) chemoreception in the oral cavity, known as fat taste, may trigger a satiety response that is homologous to FA chemoreception in the gastrointestinal tract. In addition, individuals with an impaired fat taste sensitivity are more likely to have an impaired satiety response. This study aimed to assess the effect of an FA mouth rinse on self-reported appetite, and to determine if the effect is modified by fat taste sensitivity. Thirty-one participants (age, 32.0 ± 8.4 y; body mass index (BMI), 26.1 ± 8.1 kg/m<sup>2</sup>) were studied on four separate days to evaluate the effect of a 20 mM oleic acid (OA) mouth rinse (in duplicate) compared to a control (in duplicate) on self-reported appetite by using a visual analogue scale (VAS) every 30 min for three hours following a standardized low-fat breakfast. The area under the curve ratings for fullness were greater (<i>p</i> = 0.003), and those for hunger were lower (<i>p</i> = 0.002) following the OA rinse compared to the control. The effect of the OA rinse was greater in individuals who were hypersensitive to fat taste compared to moderately sensitive and hyposensitive individuals for fullness (<i>p</i> < 0.010) and hunger (<i>p</i> < 0.010) ratings. In summary, an OA mouth rinse decreases self-reported hunger and increases self-reported fullness, particularly in those who are more sensitive to fat taste. FA receptors in the oral cavity may be potential targets to regulate appetite.https://www.mdpi.com/2072-6643/12/3/678fat tastesatietymouth rinseappetitesensitivity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andrew Costanzo Catherine G Russell Simone Lewin Russell Keast |
spellingShingle |
Andrew Costanzo Catherine G Russell Simone Lewin Russell Keast A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial Nutrients fat taste satiety mouth rinse appetite sensitivity |
author_facet |
Andrew Costanzo Catherine G Russell Simone Lewin Russell Keast |
author_sort |
Andrew Costanzo |
title |
A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial |
title_short |
A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial |
title_full |
A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial |
title_fullStr |
A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial |
title_full_unstemmed |
A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial |
title_sort |
fatty acid mouth rinse decreases self-reported hunger and increases self-reported fullness in healthy australian adults: a randomized cross-over trial |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2020-03-01 |
description |
Fatty acid (FA) chemoreception in the oral cavity, known as fat taste, may trigger a satiety response that is homologous to FA chemoreception in the gastrointestinal tract. In addition, individuals with an impaired fat taste sensitivity are more likely to have an impaired satiety response. This study aimed to assess the effect of an FA mouth rinse on self-reported appetite, and to determine if the effect is modified by fat taste sensitivity. Thirty-one participants (age, 32.0 ± 8.4 y; body mass index (BMI), 26.1 ± 8.1 kg/m<sup>2</sup>) were studied on four separate days to evaluate the effect of a 20 mM oleic acid (OA) mouth rinse (in duplicate) compared to a control (in duplicate) on self-reported appetite by using a visual analogue scale (VAS) every 30 min for three hours following a standardized low-fat breakfast. The area under the curve ratings for fullness were greater (<i>p</i> = 0.003), and those for hunger were lower (<i>p</i> = 0.002) following the OA rinse compared to the control. The effect of the OA rinse was greater in individuals who were hypersensitive to fat taste compared to moderately sensitive and hyposensitive individuals for fullness (<i>p</i> < 0.010) and hunger (<i>p</i> < 0.010) ratings. In summary, an OA mouth rinse decreases self-reported hunger and increases self-reported fullness, particularly in those who are more sensitive to fat taste. FA receptors in the oral cavity may be potential targets to regulate appetite. |
topic |
fat taste satiety mouth rinse appetite sensitivity |
url |
https://www.mdpi.com/2072-6643/12/3/678 |
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