Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding
Tissue circadian clocks contribute to the regulation of physiology and metabolism. Here the authors investigate the role of the intestinal circadian clock in energy homeostasis and show that the intestinal clock acts as an accelerator in dietary fat absorption.
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Nature Publishing Group
2021-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-25674-5 |
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doaj-4350d5cd87d640bab237e0ab920e5a082021-09-12T11:46:10ZengNature Publishing GroupNature Communications2041-17232021-09-0112111510.1038/s41467-021-25674-5Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feedingFangjun Yu0Zhigang Wang1Tianpeng Zhang2Xun Chen3Haiman Xu4Fei Wang5Lianxia Guo6Min Chen7Kaisheng Liu8Baojian Wu9Institute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese MedicineDepartment of Intensive Care Unit, First Affiliated Hospital of Jinan UniversityInstitute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese MedicineCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityShenzhen People’s Hospital, The Second Clinical Medical College of Jinan UniversityInstitute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese MedicineTissue circadian clocks contribute to the regulation of physiology and metabolism. Here the authors investigate the role of the intestinal circadian clock in energy homeostasis and show that the intestinal clock acts as an accelerator in dietary fat absorption.https://doi.org/10.1038/s41467-021-25674-5 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fangjun Yu Zhigang Wang Tianpeng Zhang Xun Chen Haiman Xu Fei Wang Lianxia Guo Min Chen Kaisheng Liu Baojian Wu |
spellingShingle |
Fangjun Yu Zhigang Wang Tianpeng Zhang Xun Chen Haiman Xu Fei Wang Lianxia Guo Min Chen Kaisheng Liu Baojian Wu Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding Nature Communications |
author_facet |
Fangjun Yu Zhigang Wang Tianpeng Zhang Xun Chen Haiman Xu Fei Wang Lianxia Guo Min Chen Kaisheng Liu Baojian Wu |
author_sort |
Fangjun Yu |
title |
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding |
title_short |
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding |
title_full |
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding |
title_fullStr |
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding |
title_full_unstemmed |
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding |
title_sort |
deficiency of intestinal bmal1 prevents obesity induced by high-fat feeding |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2021-09-01 |
description |
Tissue circadian clocks contribute to the regulation of physiology and metabolism. Here the authors investigate the role of the intestinal circadian clock in energy homeostasis and show that the intestinal clock acts as an accelerator in dietary fat absorption. |
url |
https://doi.org/10.1038/s41467-021-25674-5 |
work_keys_str_mv |
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