Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding

Tissue circadian clocks contribute to the regulation of physiology and metabolism. Here the authors investigate the role of the intestinal circadian clock in energy homeostasis and show that the intestinal clock acts as an accelerator in dietary fat absorption.

Bibliographic Details
Main Authors:	Fangjun Yu, Zhigang Wang, Tianpeng Zhang, Xun Chen, Haiman Xu, Fei Wang, Lianxia Guo, Min Chen, Kaisheng Liu, Baojian Wu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-09-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-25674-5

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spelling	doaj-4350d5cd87d640bab237e0ab920e5a082021-09-12T11:46:10ZengNature Publishing GroupNature Communications2041-17232021-09-0112111510.1038/s41467-021-25674-5Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feedingFangjun Yu0Zhigang Wang1Tianpeng Zhang2Xun Chen3Haiman Xu4Fei Wang5Lianxia Guo6Min Chen7Kaisheng Liu8Baojian Wu9Institute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese MedicineDepartment of Intensive Care Unit, First Affiliated Hospital of Jinan UniversityInstitute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese MedicineCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityCollege of Pharmacy, Jinan UniversityShenzhen People’s Hospital, The Second Clinical Medical College of Jinan UniversityInstitute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese MedicineTissue circadian clocks contribute to the regulation of physiology and metabolism. Here the authors investigate the role of the intestinal circadian clock in energy homeostasis and show that the intestinal clock acts as an accelerator in dietary fat absorption.https://doi.org/10.1038/s41467-021-25674-5
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Fangjun Yu Zhigang Wang Tianpeng Zhang Xun Chen Haiman Xu Fei Wang Lianxia Guo Min Chen Kaisheng Liu Baojian Wu
spellingShingle	Fangjun Yu Zhigang Wang Tianpeng Zhang Xun Chen Haiman Xu Fei Wang Lianxia Guo Min Chen Kaisheng Liu Baojian Wu Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding Nature Communications
author_facet	Fangjun Yu Zhigang Wang Tianpeng Zhang Xun Chen Haiman Xu Fei Wang Lianxia Guo Min Chen Kaisheng Liu Baojian Wu
author_sort	Fangjun Yu
title	Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding
title_short	Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding
title_full	Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding
title_fullStr	Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding
title_full_unstemmed	Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding
title_sort	deficiency of intestinal bmal1 prevents obesity induced by high-fat feeding
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-09-01
description	Tissue circadian clocks contribute to the regulation of physiology and metabolism. Here the authors investigate the role of the intestinal circadian clock in energy homeostasis and show that the intestinal clock acts as an accelerator in dietary fat absorption.
url	https://doi.org/10.1038/s41467-021-25674-5
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Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding

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