Protective Antigen-Specific Memory B Cells Persist Years after Anthrax Vaccination and Correlate with Humoral Immunity
Anthrax Vaccine Adsorbed (AVA) generates short-lived protective antigen (PA) specific IgG that correlates with in vitro toxin neutralization and protection from Bacillus anthracis challenge. Animal studies suggest that when PA-specific IgG has waned, survival after spore challenge correlates with a...
Main Authors: | Lori Garman, Kenneth Smith, A. Darise Farris, Michael R. Nelson, Renata J. M. Engler, Judith A. James |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-08-01
|
Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/6/8/2424 |
Similar Items
-
Different mechanisms of two anti-anthrax protective antigen antibodies and function comparison between them
by: Siping Xiong, et al.
Published: (2019-11-01) -
Development of an in Vitro Potency Assay for Anti-anthrax Lethal Toxin Neutralizing Antibodies
by: Sjoerd Rijpkema, et al.
Published: (2012-01-01) -
Human monoclonal anti-protective antigen antibody for the low-dose post-exposure prophylaxis and treatment of Anthrax
by: Qi Tang, et al.
Published: (2018-12-01) -
Antibodies against Anthrax: Mechanisms of Action and Clinical Applications
by: Thibaut Pelat, et al.
Published: (2011-11-01) -
Anthrax Toxin Detection: From in Vivo Studies to Diagnostic Applications
by: Jean-Nicolas Tournier, et al.
Published: (2020-07-01)