Establishment of human embryonic stem cell WAe009-A-48 carrying a long QT syndrome mutation in SCN5A
The long QT syndrome type 3 (LQT3) is currently the 3rd most prevalent of the 15 known types of LQT syndrome. Cardiac events in LQT3 are less frequent than LQT1 and LQT2, but more likely to be fatal. LQT3 is caused by mutation in gene SCN5A, which codes for the Nav1.5 Na+ channel. Herein, we have ge...
Main Authors: | Xiaofei Yang, Fujian Wu, Jiaqi Zhong, Furong Li |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506121000404 |
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