F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome

F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome

Oxidative damage has been reported in Rett syndrome (RTT), a pervasive developmental disorder caused in up to 95% of cases by mutations in the X-linked methyl-CpG binding protein 2 gene. Herein, we have synthesized F2-dihomo-isoprostanes (F2-dihomo-IsoPs), peroxidation products from adrenic acid (22...

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Bibliographic Details
Main Authors: Claudio De Felice, Cinzia Signorini, Thierry Durand, Camille Oger, Alexandre Guy, Valérie Bultel-Poncé, Jean-Marie Galano, Lucia Ciccoli, Silvia Leoncini, Maurizio D'Esposito, Stefania Filosa, Alessandra Pecorelli, Giuseppe Valacchi, Joussef Hayek
Format: Article
Language:English
Published: Elsevier 2011-12-01
Series:Journal of Lipid Research
Subjects:
methyl-CpG binding protein 2
adrenic acid
myelin damage
autism spectrum disorders
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408338

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http://www.sciencedirect.com/science/article/pii/S0022227520408338

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