Synaptic NR2A- but not NR2B-containing NMDA receptors increase with blockade of ionotropic glutamate receptors

NMDA receptors are key molecules involved in physiological and pathophysiological brain processes such as plasticity and excitotoxicity. Neuronal activity regulates NMDA receptor levels in the cell membrane. However, little is known on which time scale this regulation occurs and whether the two main...

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Bibliographic Details
Main Authors: Jakob Von Engelhardt, Beril Doganci, Peter H Seeburg, Hannah Monyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
APV
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.02.019.2009/full