Mom knows best: the universality of maternal microbial transmission.
The sterile womb paradigm is an enduring premise in biology that human infants are born sterile. Recent studies suggest that infants incorporate an initial microbiome before birth and receive copious supplementation of maternal microbes through birth and breastfeeding. Moreover, evidence for microbi...
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doaj-43cd635e04e141408383fb2ffae2c1662021-07-02T16:27:19ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852013-01-01118e100163110.1371/journal.pbio.1001631Mom knows best: the universality of maternal microbial transmission.Lisa J FunkhouserSeth R BordensteinThe sterile womb paradigm is an enduring premise in biology that human infants are born sterile. Recent studies suggest that infants incorporate an initial microbiome before birth and receive copious supplementation of maternal microbes through birth and breastfeeding. Moreover, evidence for microbial maternal transmission is increasingly widespread across animals. This collective knowledge compels a paradigm shift—one in which maternal transmission of microbes advances from a taxonomically specialized phenomenon to a universal one in animals. It also engenders fresh views on the assembly of the microbiome, its role in animal evolution, and applications to human health and disease.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23976878/?tool=EBI |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lisa J Funkhouser Seth R Bordenstein |
spellingShingle |
Lisa J Funkhouser Seth R Bordenstein Mom knows best: the universality of maternal microbial transmission. PLoS Biology |
author_facet |
Lisa J Funkhouser Seth R Bordenstein |
author_sort |
Lisa J Funkhouser |
title |
Mom knows best: the universality of maternal microbial transmission. |
title_short |
Mom knows best: the universality of maternal microbial transmission. |
title_full |
Mom knows best: the universality of maternal microbial transmission. |
title_fullStr |
Mom knows best: the universality of maternal microbial transmission. |
title_full_unstemmed |
Mom knows best: the universality of maternal microbial transmission. |
title_sort |
mom knows best: the universality of maternal microbial transmission. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS Biology |
issn |
1544-9173 1545-7885 |
publishDate |
2013-01-01 |
description |
The sterile womb paradigm is an enduring premise in biology that human infants are born sterile. Recent studies suggest that infants incorporate an initial microbiome before birth and receive copious supplementation of maternal microbes through birth and breastfeeding. Moreover, evidence for microbial maternal transmission is increasingly widespread across animals. This collective knowledge compels a paradigm shift—one in which maternal transmission of microbes advances from a taxonomically specialized phenomenon to a universal one in animals. It also engenders fresh views on the assembly of the microbiome, its role in animal evolution, and applications to human health and disease. |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23976878/?tool=EBI |
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