Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C

Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C

A potential strategy to combat obesity and its associated complications involves modifying gene expression in adipose cells to reduce lipid accumulation. The nuclear receptor Peroxisome Proliferator-activated receptor gamma (PPARγ) is the master regulator of adipose cell differentiation and its func...

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Bibliographic Details
Main Authors: Lizcano Fernando, Romero Carolina, Diana Vargas
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2011-01-01
Series:Genetics and Molecular Biology
Subjects:
PPARγ
histones
demethylation
JMJD2C
deacetylation
adipocyte
Trichostatin A
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000100004&lng=en&tlng=en

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