Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?

Asherman syndrome is a multifaceted condition describing the partial or complete removal of the uterine cavity and/or cervical canal. It is a highly debatable topic because of its pronounced influence on both reproductive outcomes and gynaecologic symptoms. The latest reports demonstrated that traum...

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Main Authors: Bogdan Doroftei, Ana-Maria Dabuleanu, Ovidiu-Dumitru Ilie, Radu Maftei, Emil Anton, Gabriela Simionescu, Theodor Matei, Theodora Armeanu
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/10/9/706
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spelling doaj-43df4ba9ad544fed9df5ab85ec1762882020-11-25T04:02:23ZengMDPI AGDiagnostics2075-44182020-09-011070670610.3390/diagnostics10090706Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?Bogdan Doroftei0Ana-Maria Dabuleanu1Ovidiu-Dumitru Ilie2Radu Maftei3Emil Anton4Gabriela Simionescu5Theodor Matei6Theodora Armeanu7Faculty of Medicine, University of Medicine and Pharmacy “Grigore T. Popa”, University Street, No. 16, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T. Popa”, University Street, No. 16, 700115 Iasi, RomaniaDepartment of Research, Faculty of Biology, Alexandru Ioan Cuza University, Carol I Avenue, No. 20A, 700505 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T. Popa”, University Street, No. 16, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T. Popa”, University Street, No. 16, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T. Popa”, University Street, No. 16, 700115 Iasi, RomaniaClinical Hospital of Obstetrics and Gynecology “Cuza Voda”, Cuza Voda Street, No. 34, 700038 Iasi, RomaniaClinical Hospital of Obstetrics and Gynecology “Cuza Voda”, Cuza Voda Street, No. 34, 700038 Iasi, RomaniaAsherman syndrome is a multifaceted condition describing the partial or complete removal of the uterine cavity and/or cervical canal. It is a highly debatable topic because of its pronounced influence on both reproductive outcomes and gynaecologic symptoms. The latest reports demonstrated that trauma to the endometrium is the main cause of intrauterine adhesion formation. Left untreated, such adhesions gradually lead to a range of repercussions ranging from mild to severe. Considering the lack of non-invasive approaches, the advent of hysteroscopy has revolutionized the entire field, being otherwise considered the most efficient tool offering new directions and amplifying the chances of treating the Asherman syndrome.https://www.mdpi.com/2075-4418/10/9/706Asherman syndromeintrauterine adhesionsintrauterine synechiaehysteroscopy
collection DOAJ
language English
format Article
sources DOAJ
author Bogdan Doroftei
Ana-Maria Dabuleanu
Ovidiu-Dumitru Ilie
Radu Maftei
Emil Anton
Gabriela Simionescu
Theodor Matei
Theodora Armeanu
spellingShingle Bogdan Doroftei
Ana-Maria Dabuleanu
Ovidiu-Dumitru Ilie
Radu Maftei
Emil Anton
Gabriela Simionescu
Theodor Matei
Theodora Armeanu
Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?
Diagnostics
Asherman syndrome
intrauterine adhesions
intrauterine synechiae
hysteroscopy
author_facet Bogdan Doroftei
Ana-Maria Dabuleanu
Ovidiu-Dumitru Ilie
Radu Maftei
Emil Anton
Gabriela Simionescu
Theodor Matei
Theodora Armeanu
author_sort Bogdan Doroftei
title Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?
title_short Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?
title_full Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?
title_fullStr Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?
title_full_unstemmed Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?
title_sort mini-review of the new therapeutic possibilities in asherman syndrome—where are we after one hundred and twenty-six years?
publisher MDPI AG
series Diagnostics
issn 2075-4418
publishDate 2020-09-01
description Asherman syndrome is a multifaceted condition describing the partial or complete removal of the uterine cavity and/or cervical canal. It is a highly debatable topic because of its pronounced influence on both reproductive outcomes and gynaecologic symptoms. The latest reports demonstrated that trauma to the endometrium is the main cause of intrauterine adhesion formation. Left untreated, such adhesions gradually lead to a range of repercussions ranging from mild to severe. Considering the lack of non-invasive approaches, the advent of hysteroscopy has revolutionized the entire field, being otherwise considered the most efficient tool offering new directions and amplifying the chances of treating the Asherman syndrome.
topic Asherman syndrome
intrauterine adhesions
intrauterine synechiae
hysteroscopy
url https://www.mdpi.com/2075-4418/10/9/706
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