Melleins—Intriguing Natural Compounds
Melleins are 3,4-dihydroisocoumarins mainly produced by fungi, but also by plants, insects and bacteria. These specialized metabolites play important roles in the life cycles of the producers and they are involved in many biochemical and ecological processes. This review outlines the isolation and c...
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MDPI AG
2020-05-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/10/5/772 |
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doaj-43fe999d76854ca287ee2bab0a2e047d2020-11-25T02:53:56ZengMDPI AGBiomolecules2218-273X2020-05-011077277210.3390/biom10050772Melleins—Intriguing Natural CompoundsPierluigi Reveglia0Marco Masi1Antonio Evidente2Dipartimento di Scienze Chimiche, Università di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, ItalyDipartimento di Scienze Chimiche, Università di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, ItalyDipartimento di Scienze Chimiche, Università di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, ItalyMelleins are 3,4-dihydroisocoumarins mainly produced by fungi, but also by plants, insects and bacteria. These specialized metabolites play important roles in the life cycles of the producers and they are involved in many biochemical and ecological processes. This review outlines the isolation and chemical and biological characterizations of natural-occurring melleins from the first report of (<i>R</i>)-mellein in 1933 to the most recent advances in their characterization in 2019. In addition, the pathways that could be involved in mellein biosynthesis are discussed, along with the enzymes and genes involved.https://www.mdpi.com/2218-273X/10/5/7723,4-dihydroisocoumarinsmelleinschemical characterizationbiological activitiesbiosynthesis |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Pierluigi Reveglia Marco Masi Antonio Evidente |
| spellingShingle |
Pierluigi Reveglia Marco Masi Antonio Evidente Melleins—Intriguing Natural Compounds Biomolecules 3,4-dihydroisocoumarins melleins chemical characterization biological activities biosynthesis |
| author_facet |
Pierluigi Reveglia Marco Masi Antonio Evidente |
| author_sort |
Pierluigi Reveglia |
| title |
Melleins—Intriguing Natural Compounds |
| title_short |
Melleins—Intriguing Natural Compounds |
| title_full |
Melleins—Intriguing Natural Compounds |
| title_fullStr |
Melleins—Intriguing Natural Compounds |
| title_full_unstemmed |
Melleins—Intriguing Natural Compounds |
| title_sort |
melleins—intriguing natural compounds |
| publisher |
MDPI AG |
| series |
Biomolecules |
| issn |
2218-273X |
| publishDate |
2020-05-01 |
| description |
Melleins are 3,4-dihydroisocoumarins mainly produced by fungi, but also by plants, insects and bacteria. These specialized metabolites play important roles in the life cycles of the producers and they are involved in many biochemical and ecological processes. This review outlines the isolation and chemical and biological characterizations of natural-occurring melleins from the first report of (<i>R</i>)-mellein in 1933 to the most recent advances in their characterization in 2019. In addition, the pathways that could be involved in mellein biosynthesis are discussed, along with the enzymes and genes involved. |
| topic |
3,4-dihydroisocoumarins melleins chemical characterization biological activities biosynthesis |
| url |
https://www.mdpi.com/2218-273X/10/5/772 |
| work_keys_str_mv |
AT pierluigireveglia melleinsintriguingnaturalcompounds AT marcomasi melleinsintriguingnaturalcompounds AT antonioevidente melleinsintriguingnaturalcompounds |
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