Profiling surface proteins on individual exosomes using a proximity barcoding assay

The use of antibodies to capture and profile exosomes limits the number of target proteins that can be detected. Here the authors develop a proximity-dependent barcoding assay that allows profiling of 38 surface proteins on individual exosomes from heterogeneous samples such as serum and seminal flu...

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Bibliographic Details
Main Authors: Di Wu, Junhong Yan, Xia Shen, Yu Sun, Måns Thulin, Yanling Cai, Lotta Wik, Qiujin Shen, Johan Oelrich, Xiaoyan Qian, K. Louise Dubois, K. Göran Ronquist, Mats Nilsson, Ulf Landegren, Masood Kamali-Moghaddam
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11486-1