Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysisResearch in context
Background: Redox metabolism is often considered a potential target for cancer treatment, but a systematic examination of redox responses in hepatocellular carcinoma (HCC) is missing. Methods: Here, we employed systems biology and biological network analyses to reveal key roles of genes associated w...
Main Authors: | Rui Benfeitas, Gholamreza Bidkhori, Bani Mukhopadhyay, Martina Klevstig, Muhammad Arif, Cheng Zhang, Sunjae Lee, Resat Cinar, Jens Nielsen, Mathias Uhlen, Jan Boren, George Kunos, Adil Mardinoglu |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-02-01
|
Series: | EBioMedicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396418306352 |
Similar Items
-
New Challenges to Study Heterogeneity in Cancer Redox Metabolism
by: Rui Benfeitas, et al.
Published: (2017-07-01) -
Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma
by: Gholamreza Bidkhori, et al.
Published: (2018-07-01) -
ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling
by: Cheng Zhang, et al.
Published: (2018-09-01) -
Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization
by: Elias Björnson, et al.
Published: (2015-12-01) -
Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling
by: Dorines Rosario, et al.
Published: (2018-06-01)