The Expression of HMGB1 in Bone Marrow MSCs Is Upregulated by Hypoxia with Regulatory Effects on the Apoptosis and Adhesion

Background and Aims. Hypoxia regulates the survival of mesenchymal stem cells (MSCs) but the mechanism is unclear. In hypoxia, the level of high mobility group box 1 (HMGB1) was increased in many cells which may be involved in the regulation of cell biology. The aim is to determine whether hypoxia a...

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Bibliographic Details
Main Authors: Mei-Yun Tan, Cai-Dong Zhang, Bo Xia, Jiang Guo, Zhong-Wei Fan, Tian-Hao Wu, Sen Wang, Shao-Feng Liu, Li Deng, Xing Guo, Yong-Can Huang
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/4598927

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