Gastric Cancer in South East of Iran

• Main Authors: Mohammadali Mashhadi, K Nazem, MJ Abdollahinejad
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2009-10-01
• Series: International Journal of Hematology-Oncology and Stem Cell Research
• Subjects: Gastric cancer,South east of iran
• Online Access: http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16109.pdf&manuscript_id=16109

"nIntroduction: Gastric cancer is the second most common GI malignancy in Zahedan. This investigation was undertaken to define the demographic, clinicopathological, and prognostic factors relevant to patients with gastric adenocarcinoma. "nMethods: We did a retrospective study of 100 patients with gastric cancer who had been at Ali Ebne Abitaleb Hospital and Khatam al Anbia Hospital in 2004-2006. Data analysis was done using the Kaplan-Meier method and the Cox proportional hazard model. "nResults: The mean patient age at diagnosis was 50 years (range= 28-83 years), and 68% were male. The male-to-female ratio of patients was 2.1/1. Ninety-six percent of the patients were Iranian and in the Balouch ethnic group was presented more than the Sistani ethnic group, and 4% were Afghan. Five percent of the patients reported a family history of gastric cancer. 67 patients (67 %) presented with stages III or IV disease, whereas 33 patients, with stages I or II disease. Poorly differentiated lesions were present in 71%. In 16 patients, metastasis was seen. Common chief complaint was abdominal pain in epigastria (58 %). Survival data was available in 78 cases. The median survival was 8 months. "nConclusion: Gastric cancer is the second most common GI malignancies in Zahedan. This pattern is different from other regions in Iran that gastric cancer is most common GI malignancies. This fact will need to be confirmed by a longer period of observation.