The Skin-Whitening Effects of Ectoine via the Suppression of α-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes
Ultraviolet A (UVA)-irradiation induced reactive oxygen species (ROS) production mediates excessive melanogenesis in skin cells leading to pigmentation. We demonstrated the depigmenting and anti-melanogenic effects of Ectoine, a natural bacterial osmolyte, in UVA-irradiated human (HaCaT) keratinocyt...
Main Authors: | You-Cheng Hseu, Xuan-Zao Chen, Yugandhar Vudhya Gowrisankar, Hung-Rong Yen, Jing-Yuan Chuang, Hsin-Ling Yang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-01-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/9/1/63 |
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