Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers
Platelet rich plasma (PRP) is blood plasma with a platelet concentration above baseline. When activated, PRP releases growth factors involved in all stages of wound healing, potentially boosting the healing process. To expand our knowledge of the effectiveness of PRP, it is crucial to know the conte...
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MDPI AG
2019-01-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | http://www.mdpi.com/1422-0067/20/2/288 |
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doaj-4493fe61003545bba21838ad1b739e6c2020-11-25T01:52:53ZengMDPI AGInternational Journal of Molecular Sciences1422-00672019-01-0120228810.3390/ijms20020288ijms20020288Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy VolunteersRoos E. Marck0Kim L. M. Gardien1Marcel Vlig2Roelf S. Breederveld3Esther Middelkoop4Department of Plastic, Reconstructive & Hand Surgery, Amsterdam UMC, University of Amsterdam, 1081 HV Amsterdam, The NetherlandsBurn Center, Red Cross Hospital, 1942 LE Beverwijk, The NetherlandsAssociation of Dutch Burn Centers, 1942 LE Beverwijk, The NetherlandsBurn Center, Red Cross Hospital, 1942 LE Beverwijk, The NetherlandsBurn Center, Red Cross Hospital, 1942 LE Beverwijk, The NetherlandsPlatelet rich plasma (PRP) is blood plasma with a platelet concentration above baseline. When activated, PRP releases growth factors involved in all stages of wound healing, potentially boosting the healing process. To expand our knowledge of the effectiveness of PRP, it is crucial to know the content and composition of PRP products. In this study, growth factor quantification measurements of PRP from burn patients and gender- and age-matched controls were performed. The PRP of burn patients showed levels of growth factors comparable to those of the PRP of healthy volunteers. Considerable intra-individual variation in growth factor content was found. However, a correlation was found between the platelet count of the PRP and most of the growth factors measured.http://www.mdpi.com/1422-0067/20/2/288plateletsburnsgrowth factorsplatelet rich plasmaquantification |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Roos E. Marck Kim L. M. Gardien Marcel Vlig Roelf S. Breederveld Esther Middelkoop |
| spellingShingle |
Roos E. Marck Kim L. M. Gardien Marcel Vlig Roelf S. Breederveld Esther Middelkoop Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers International Journal of Molecular Sciences platelets burns growth factors platelet rich plasma quantification |
| author_facet |
Roos E. Marck Kim L. M. Gardien Marcel Vlig Roelf S. Breederveld Esther Middelkoop |
| author_sort |
Roos E. Marck |
| title |
Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers |
| title_short |
Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers |
| title_full |
Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers |
| title_fullStr |
Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers |
| title_full_unstemmed |
Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers |
| title_sort |
growth factor quantification of platelet-rich plasma in burn patients compared to matched healthy volunteers |
| publisher |
MDPI AG |
| series |
International Journal of Molecular Sciences |
| issn |
1422-0067 |
| publishDate |
2019-01-01 |
| description |
Platelet rich plasma (PRP) is blood plasma with a platelet concentration above baseline. When activated, PRP releases growth factors involved in all stages of wound healing, potentially boosting the healing process. To expand our knowledge of the effectiveness of PRP, it is crucial to know the content and composition of PRP products. In this study, growth factor quantification measurements of PRP from burn patients and gender- and age-matched controls were performed. The PRP of burn patients showed levels of growth factors comparable to those of the PRP of healthy volunteers. Considerable intra-individual variation in growth factor content was found. However, a correlation was found between the platelet count of the PRP and most of the growth factors measured. |
| topic |
platelets burns growth factors platelet rich plasma quantification |
| url |
http://www.mdpi.com/1422-0067/20/2/288 |
| work_keys_str_mv |
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