A Calpain-Like Protein Is Involved in the Execution Phase of Programmed Cell Death of Entamoeba histolytica

A Calpain-Like Protein Is Involved in the Execution Phase of Programmed Cell Death of Entamoeba histolytica

Oxygen or nitrogen oxidative species and chemical stress induce the programmed cell death (PCD) of Entamoeba histolytica trophozoites. PCD caused by the aminoglycoside G418 is reduced by incubation with the cysteine protease inhibitor E-64; however, no typical caspases or metacaspases have been dete...

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Bibliographic Details
Main Authors: Tania Domínguez-Fernández, Mario Alberto Rodríguez, Virginia Sánchez Monroy, Consuelo Gómez García, Olivia Medel, David Guillermo Pérez Ishiwara
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Entamoeba histolytica
cysteine proteases
programmed cell death
protein overexpression
calcium binding sites
calpain
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00339/full

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