The Controversial Role of Retinoic Acid in Fibrotic Diseases: Analysis of Involved Signaling Pathways
Fibrotic diseases, such as liver, pulmonary and renal fibrosis, are common end-stage conditions and represent a major global health problem. Furthermore, effective therapeutic measures are presently unavailable. Extracellular matrix accumulation is the most prominent characteristic in the pathogenes...
Main Authors: | Yuan-Han Qin, Gregor P. C. Drummen, Tian-Biao Zhou |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-12-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/14/1/226 |
Similar Items
-
All-Trans Retinoic Acid Attenuates Fibrotic Processes by Downregulating TGF-β1/Smad3 in Early Diabetic Nephropathy
by: Edith Sierra-Mondragon, et al.
Published: (2019-09-01) -
Identification of influential proteins in the classical retinoic acid signaling pathway
by: Hamed Ghaffari, et al.
Published: (2018-10-01) -
Anti-fibrotic activity of medicinal plants
by: Usman Akhtar, et al.
Published: (2017-11-01) -
Therapeutic Potential of Polyphenols in Cardiac Fibrosis
by: Ning Zhang, et al.
Published: (2018-02-01) -
T Cells in Fibrosis and Fibrotic Diseases
by: Mengjuan Zhang, et al.
Published: (2020-06-01)