Targeting Crosstalk between Nrf-2, NF-κB and Androgen Receptor Signaling in Prostate Cancer

Targeting Crosstalk between Nrf-2, NF-κB and Androgen Receptor Signaling in Prostate Cancer

Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in the initiation, development and progression of prostate cancer (PCa). Numerous papers in the literature have documented the interconnection between oxidative stress and inflammation; and how antioxidants can c...

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Bibliographic Details
Main Authors: Namrata Khurana, Suresh C. Sikka
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Cancers
Subjects:
prostate cancer
castration resistant prostate cancer (CRPC)
oxidative stress
inflammation
androgen receptor (AR)
AR-V7
Nrf-2
NF-κB
sulforaphane
curcumin and bardoxolone methyl
Online Access:http://www.mdpi.com/2072-6694/10/10/352

Internet

http://www.mdpi.com/2072-6694/10/10/352

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