Revisiting the Tissue Microenvironment of Infectious Mononucleosis: Identification of EBV Infection in T Cells and Deep Characterization of Immune Profiles
To aid understanding of primary EBV infection, we have performed an in depth analysis of EBV-infected cells and of local immune cells in tonsils from infectious mononucleosis (IM) patients. We show that EBV is present in approximately 50% of B-cells showing heterogeneous patterns of latent viral gen...
Main Authors: | Mário Henrique M. Barros, Gabriela Vera-Lozada, Priscilla Segges, Rocio Hassan, Gerald Niedobitek |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-02-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.00146/full |
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