Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)

The optimal dose of medetomidine-ketamine-buprenorphine was determined in 25 Cape ground squirrels (Xerus inauris) undergoing surgical implantation of a temperature logger into the abdominal cavity. At the end of anaesthesia, the squirrels were given atipamezole intramuscularly to reverse the effect...

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Main Authors:	K. E. Joubert, T. Serfontein, M. Scantlebury, M B Manjerovic, P. W. Bateman, N. C. Bennett, J. M. Waterman
Format:	Article
Language:	English
Published:	AOSIS 2011-04-01
Series:	Journal of the South African Veterinary Association
Online Access:	https://jsava.co.za/index.php/jsava/article/view/41

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spelling	doaj-44e01508a03f429eaf0098af9aa8f6632020-11-24T22:01:58ZengAOSISJournal of the South African Veterinary Association1019-91282224-94352011-04-01822949610.4102/jsava.v82i2.4123Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)K. E. Joubert0T. Serfontein1M. Scantlebury2M B Manjerovic3P. W. Bateman4M B Manjerovic5P. W. Bateman6N. C. Bennett7J. M. Waterman8Pharmacology, Department of Paraclinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa.Anaesthesiology, Onderstepoort Academic Veterinary Hospital, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa.School of Biological Sciences, Queen’s University Belfast, Belfast BT9 7BL, UK. Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa.Department of Biology, University of Central Florida, Orlando, FL 32816-2368, USA.Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South AfricaDepartment of Zoology and Entomology, University of Pretoria, Pretoria 0002, South AfricaDepartment of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa.Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa.Department of Biological Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.The optimal dose of medetomidine-ketamine-buprenorphine was determined in 25 Cape ground squirrels (Xerus inauris) undergoing surgical implantation of a temperature logger into the abdominal cavity. At the end of anaesthesia, the squirrels were given atipamezole intramuscularly to reverse the effects of medetomidine. The mean dose of medetomidine was 67.6±9.2 μg/kg, ketamine 13.6±1.9 mg/kg and buprenorphine 0.5±0.06 μg/kg. Induction time was 3.1 ± 1.4 min. This produced surgical anaesthesia for 21± 4.2 min. Atipamezole 232±92 μg/kg produced a rapid recovery. Squirrels were sternally recumbent in 3.5 ± 2.2 min.https://jsava.co.za/index.php/jsava/article/view/41
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	K. E. Joubert T. Serfontein M. Scantlebury M B Manjerovic P. W. Bateman M B Manjerovic P. W. Bateman N. C. Bennett J. M. Waterman
spellingShingle	K. E. Joubert T. Serfontein M. Scantlebury M B Manjerovic P. W. Bateman M B Manjerovic P. W. Bateman N. C. Bennett J. M. Waterman Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris) Journal of the South African Veterinary Association
author_facet	K. E. Joubert T. Serfontein M. Scantlebury M B Manjerovic P. W. Bateman M B Manjerovic P. W. Bateman N. C. Bennett J. M. Waterman
author_sort	K. E. Joubert
title	Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)
title_short	Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)
title_full	Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)
title_fullStr	Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)
title_full_unstemmed	Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)
title_sort	determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the cape ground squirrel (xerus inauris)
publisher	AOSIS
series	Journal of the South African Veterinary Association
issn	1019-9128 2224-9435
publishDate	2011-04-01
description	The optimal dose of medetomidine-ketamine-buprenorphine was determined in 25 Cape ground squirrels (Xerus inauris) undergoing surgical implantation of a temperature logger into the abdominal cavity. At the end of anaesthesia, the squirrels were given atipamezole intramuscularly to reverse the effects of medetomidine. The mean dose of medetomidine was 67.6±9.2 μg/kg, ketamine 13.6±1.9 mg/kg and buprenorphine 0.5±0.06 μg/kg. Induction time was 3.1 ± 1.4 min. This produced surgical anaesthesia for 21± 4.2 min. Atipamezole 232±92 μg/kg produced a rapid recovery. Squirrels were sternally recumbent in 3.5 ± 2.2 min.
url	https://jsava.co.za/index.php/jsava/article/view/41
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Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)

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