Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological Diseases

One of the main directions in the development of modern electroanalytical chemistry is the development of new effective methods for research and analysis of biological objects, particularly, human blood serum. The creation of new electrochemical sensors is a promising approach, which has determined...

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Main Authors: Olesya A. Voronova, Elena I. Korotkova, Evgenii V. Plotnikov, Alina V. Geraskevich, Nadegda G. Kataeva, Elena V. Dorozhko, Irina S. Gamayurova, Olga I. Lipskikh, Ksenia V. Derina
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/9/5/103
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spelling doaj-44e24d4953e348df83864f88103f6a5b2021-05-31T23:21:46ZengMDPI AGChemosensors2227-90402021-05-01910310310.3390/chemosensors9050103Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological DiseasesOlesya A. Voronova0Elena I. Korotkova1Evgenii V. Plotnikov2Alina V. Geraskevich3Nadegda G. Kataeva4Elena V. Dorozhko5Irina S. Gamayurova6Olga I. Lipskikh7Ksenia V. Derina8Division for Chemical Engineering, School of Earth Sciences and Engineering, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaDivision for Chemical Engineering, School of Earth Sciences and Engineering, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaResearch School of Chemistry and Applied Biomedical Sciences, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaDivision for Chemical Engineering, School of Earth Sciences and Engineering, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaDepartment of Neurology and Neurosurgery, Siberian State Medical University, 634050 Tomsk, RussiaDivision for Chemical Engineering, School of Earth Sciences and Engineering, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaDivision for Chemical Engineering, School of Earth Sciences and Engineering, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaDivision for Chemical Engineering, School of Earth Sciences and Engineering, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaDivision for Chemical Engineering, School of Earth Sciences and Engineering, National Research Tomsk Polytechnic University, 634050 Tomsk, RussiaOne of the main directions in the development of modern electroanalytical chemistry is the development of new effective methods for research and analysis of biological objects, particularly, human blood serum. The creation of new electrochemical sensors is a promising approach, which has determined several main directions in applied voltammetry in the field of chemical analytical control. In this work, the dynamics and parameters of total antioxidant activity of human serum blood of patients with chronic cerebral ischemia, during treatment with pharmaceutical drugs Mexidol, Cavinton Comfort, and Cytoflavin was tested by cathode voltammetry with a model process of oxygen electroreduction, using a new electrochemical sensor.https://www.mdpi.com/2227-9040/9/5/103glassy carbon electrodephthalocyanineantioxidantsvoltammetry
collection DOAJ
language English
format Article
sources DOAJ
author Olesya A. Voronova
Elena I. Korotkova
Evgenii V. Plotnikov
Alina V. Geraskevich
Nadegda G. Kataeva
Elena V. Dorozhko
Irina S. Gamayurova
Olga I. Lipskikh
Ksenia V. Derina
spellingShingle Olesya A. Voronova
Elena I. Korotkova
Evgenii V. Plotnikov
Alina V. Geraskevich
Nadegda G. Kataeva
Elena V. Dorozhko
Irina S. Gamayurova
Olga I. Lipskikh
Ksenia V. Derina
Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological Diseases
Chemosensors
glassy carbon electrode
phthalocyanine
antioxidants
voltammetry
author_facet Olesya A. Voronova
Elena I. Korotkova
Evgenii V. Plotnikov
Alina V. Geraskevich
Nadegda G. Kataeva
Elena V. Dorozhko
Irina S. Gamayurova
Olga I. Lipskikh
Ksenia V. Derina
author_sort Olesya A. Voronova
title Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological Diseases
title_short Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological Diseases
title_full Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological Diseases
title_fullStr Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological Diseases
title_full_unstemmed Voltammetric Study of the Total Activity of Antioxidants in the Blood Serum of Patients with Neurological Diseases
title_sort voltammetric study of the total activity of antioxidants in the blood serum of patients with neurological diseases
publisher MDPI AG
series Chemosensors
issn 2227-9040
publishDate 2021-05-01
description One of the main directions in the development of modern electroanalytical chemistry is the development of new effective methods for research and analysis of biological objects, particularly, human blood serum. The creation of new electrochemical sensors is a promising approach, which has determined several main directions in applied voltammetry in the field of chemical analytical control. In this work, the dynamics and parameters of total antioxidant activity of human serum blood of patients with chronic cerebral ischemia, during treatment with pharmaceutical drugs Mexidol, Cavinton Comfort, and Cytoflavin was tested by cathode voltammetry with a model process of oxygen electroreduction, using a new electrochemical sensor.
topic glassy carbon electrode
phthalocyanine
antioxidants
voltammetry
url https://www.mdpi.com/2227-9040/9/5/103
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