The Role of T Cells Reactive to the Cathelicidin Antimicrobial Peptide LL-37 in Acute Coronary Syndrome and Plaque Calcification

The Role of T Cells Reactive to the Cathelicidin Antimicrobial Peptide LL-37 in Acute Coronary Syndrome and Plaque Calcification

The human cationic anti-microbial peptide LL-37 is a T cell self-antigen in patients with psoriasis, who have increased risk of cardiovascular events. However, the role of LL-37 as a T cell self-antigen in the context of atherosclerosis remains unclear. The objective of this study was to test for th...

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Bibliographic Details
Main Authors: Fernando Chernomordik, Bojan Cercek, Wai Man Lio, Peter M. Mihailovic, Juliana Yano, Romana Herscovici, Xiaoning Zhao, Jianchang Zhou, Kuang-Yuh Chyu, Prediman K. Shah, Paul C. Dimayuga
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
acute coronary syndrome
T cells
atherosclerosis
cathelicidin
LL-37
mCRAMP
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.575577/full

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