Different conformations of nascent polypeptides during translocation across the ER membrane

<p>Abstract</p> <p>Background</p> <p>In eukaryotic cells, proteins are translocated across the ER membrane through a continuous ribosome-translocon channel. It is unclear to what extent proteins can fold already within the ribosome-translocon channel, and previous studi...

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Bibliographic Details
Main Authors: Whitley Paul, Nilsson IngMarie, Mingarro Ismael, von Heijne Gunnar
Format: Article
Language:English
Published: BMC 2000-12-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/1/3