Allosteric coupling of sub-millisecond clamshell motions in ionotropic glutamate receptor ligand-binding domains
Rajab et al. study the dynamics of closure of ligand binding domains (LBD) of the three major ionotropic glutamate receptor subtypes. They find pronounced sub-millisecond fluctuations in the apo state of LBDs from all three sub-types and reveal a pathway of allosteric communication in LBD dynamics a...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-09-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02605-0 |