Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis.
Septins (SEPTs) form a family of GTP-binding proteins implicated in cytoskeleton and membrane organization, cell division and host/pathogen interactions. The precise function of many family members remains elusive. We show that SEPT6 and SEPT7 complexes bound to F-actin regulate protein sorting duri...
Main Authors: | Sofia Traikov, Christoph Stange, Thomas Wassmer, Perrine Paul-Gilloteaux, Jean Salamero, Graça Raposo, Bernard Hoflack |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4224394?pdf=render |
Similar Items
-
In silico docking of forchlorfenuron (FCF) to septins suggests that FCF interferes with GTP binding.
by: Dimitrios Angelis, et al.
Published: (2014-01-01) -
Septins and Bacterial Infection
by: Vincenzo Torraca, et al.
Published: (2016-11-01) -
Protein Kinase A-Mediated Septin7 Phosphorylation Disrupts Septin Filaments and Ciliogenesis
by: Han-Yu Wang, et al.
Published: (2021-02-01) -
Glucose starvation triggers filamentous septin assemblies in an S. pombe septin-2 deletion mutant
by: Minghua Liu, et al.
Published: (2019-01-01) -
Understanding the plant ESCRT machinery and its role in tombusvirus-induced mitochondrial multivesicular body biogenesis
by: Richardson, Lynn
Published: (2012)