Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes
Cooperative signalling between receptor tyrosine kinases (RTKs) and integrins is thought to occur at the cell surface. Here the authors show that β1 integrin influences signalling of an RTK, c-Met, from a novel intracellular compartment they call autophagy-related endomembranes.
Main Authors: | Rachel Barrow-McGee, Naoki Kishi, Carine Joffre, Ludovic Ménard, Alexia Hervieu, Bakhouche A. Bakhouche, Alejandro J. Noval, Anja Mai, Camilo Guzmán, Luisa Robbez-Masson, Xavier Iturrioz, James Hulit, Caroline H. Brennan, Ian R. Hart, Peter J. Parker, Johanna Ivaska, Stéphanie Kermorgant |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11942 |
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