Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development
Abstract Despite the advances in intensive chemotherapy regimens and targeted therapies, overall survival (OS) of acute myeloid leukemia (AML) remains unfavorable due to inevitable chemotherapy resistance and high relapse rate, which mainly caused by the persistence existence of leukemia stem cells...
Main Authors: | Yiyi Yao, Fenglin Li, Jiansong Huang, Jie Jin, Huafeng Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
|
Series: | Experimental Hematology & Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40164-021-00233-2 |
Similar Items
-
The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities
by: Samantha Bruno, et al.
Published: (2021-06-01) -
The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia
by: Marilena Ciciarello, et al.
Published: (2019-10-01) -
Alterations of adiponectin gene expression in bone marrow of acute myeloid leukemia
by: Seyed Hossein Abtahi, et al.
Published: (2020-04-01) -
Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang
by: Hong-Sheng Zhou, et al.
Published: (2016-06-01) -
Bone Marrow Microenvironment in Acute Myleoid Leukemia
by: Chandran, Priya
Published: (2013)