Intermittent exposure to xenon protects against gentamicin-induced nephrotoxicity.

Intermittent exposure to xenon protects against gentamicin-induced nephrotoxicity.

Aminoglycoside antibiotics, especially gentamicin, are widely used to treat Gram-negative infections due to their efficacy and low cost. Nevertheless the use of gentamicin is limited by its major side effect, nephrotoxicity. Xenon (Xe) provided substantial organoprotective effects in acute injury of...

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Bibliographic Details
Main Authors: Ping Jia, Jie Teng, Jianzhou Zou, Yi Fang, Suhua Jiang, Xiaofang Yu, Alison J Kriegel, Mingyu Liang, Xiaoqiang Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667819?pdf=render

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