The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice

The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice

BackgroundAs the main ingredient of Crocus sativus L. (Iridaceae) extract, crocin- I (CR) has been reported to show various pharmacological activities. The aim of this study was to investigate the hypoglycemic and renal protection properties of CR in db/db mice.MethodsEight-week-old db/db mice were...

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Bibliographic Details
Main Authors: Ye Qiu, Xue Jiang, Danping Liu, Zichun Deng, Weiwei Hu, Zhiping Li, Yuxin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
crocin
diabetes
diabetic nephropathy
oxidative stress
inflammation
Nrf2 signaling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00541/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00541/full

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