Pt(IV)/Re(I) Chitosan Conjugates as a Flexible Platform for the Transport of Therapeutic and/or Diagnostic Anticancer Agents

Pt(IV)/Re(I) Chitosan Conjugates as a Flexible Platform for the Transport of Therapeutic and/or Diagnostic Anticancer Agents

New chitosan derivatives modified with (3-carboxypropyl)trimethylammonium chloride (1) and coupled with (OC-6-44)-diammine(4-carboxypropanoato)dichloridoethanolatoplatinum(IV) (2), were synthesized and their preliminary biological evaluation carried out in human tumor cells. Some of these derivative...

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Bibliographic Details
Main Authors: Elisabetta Gabano, Letícia do Quental, Elena Perin, Francisco Silva, Paula Raposinho, António Paulo, Mauro Ravera
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Inorganics
Subjects:
theranostics
platinum prodrugs
rhenium complexes
chitosan
drug targeting and delivery
Online Access:https://www.mdpi.com/2304-6740/6/1/4

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