Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging Condition

Penile calciphylaxis is a rare phenomenon of penile necrosis observed in patients with hemodialysis-dependent end-stage renal failure. Multiple treatments have been proposed including conservative management, surgical debridement and penectomy; yet, the prognosis remains extremely poor. Here, we des...

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Main Authors: Rebecca A. Campbell, Laith M. Alzweri, Nikolai A. Sopko, Katarzyna J. Macura, Arthur L. Burnett
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442017300190
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spelling doaj-459ef84551404e398a34b086122fd22f2020-11-24T22:02:00ZengElsevierUrology Case Reports2214-44202017-07-0113C11311610.1016/j.eucr.2017.03.008Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging ConditionRebecca A. Campbell0Laith M. Alzweri1Nikolai A. Sopko2Katarzyna J. Macura3Arthur L. Burnett4Case Western Reserve University School of Medicine, 11100 Euclid Ave, Cleveland, OH 44106, USAThe James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USAThe James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USAThe James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USAThe James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USAPenile calciphylaxis is a rare phenomenon of penile necrosis observed in patients with hemodialysis-dependent end-stage renal failure. Multiple treatments have been proposed including conservative management, surgical debridement and penectomy; yet, the prognosis remains extremely poor. Here, we describe a patient with protracted resolution of dry gangrene of the glans, which failed conservative management of wound care and pain management. Radiological studies revealed extensive calcification of abdominal aorta and branching vessels including the penile arteries. Due to intolerable pain, the patient required total penectomy. Earlier surgical intervention guided by findings on radiological studies may improve quality of life in this population.http://www.sciencedirect.com/science/article/pii/S2214442017300190Penile calciphylaxisPenile gangrenePenile necrosisPenectomy
collection DOAJ
language English
format Article
sources DOAJ
author Rebecca A. Campbell
Laith M. Alzweri
Nikolai A. Sopko
Katarzyna J. Macura
Arthur L. Burnett
spellingShingle Rebecca A. Campbell
Laith M. Alzweri
Nikolai A. Sopko
Katarzyna J. Macura
Arthur L. Burnett
Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging Condition
Urology Case Reports
Penile calciphylaxis
Penile gangrene
Penile necrosis
Penectomy
author_facet Rebecca A. Campbell
Laith M. Alzweri
Nikolai A. Sopko
Katarzyna J. Macura
Arthur L. Burnett
author_sort Rebecca A. Campbell
title Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging Condition
title_short Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging Condition
title_full Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging Condition
title_fullStr Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging Condition
title_full_unstemmed Penile Calciphylaxis: The Use of Radiological Investigations in the Management of a Rare and Challenging Condition
title_sort penile calciphylaxis: the use of radiological investigations in the management of a rare and challenging condition
publisher Elsevier
series Urology Case Reports
issn 2214-4420
publishDate 2017-07-01
description Penile calciphylaxis is a rare phenomenon of penile necrosis observed in patients with hemodialysis-dependent end-stage renal failure. Multiple treatments have been proposed including conservative management, surgical debridement and penectomy; yet, the prognosis remains extremely poor. Here, we describe a patient with protracted resolution of dry gangrene of the glans, which failed conservative management of wound care and pain management. Radiological studies revealed extensive calcification of abdominal aorta and branching vessels including the penile arteries. Due to intolerable pain, the patient required total penectomy. Earlier surgical intervention guided by findings on radiological studies may improve quality of life in this population.
topic Penile calciphylaxis
Penile gangrene
Penile necrosis
Penectomy
url http://www.sciencedirect.com/science/article/pii/S2214442017300190
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