Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy
Purpose: To compare the outcomes and complications of alcohol-assisted versus mechanical corneal epithelial debridement for photorefractive keratectomy (PRK). Methods: This randomized controlled trial included 1,250 eyes of 625 patients undergoing PRK for correction of myopia and myopic astigmatism...
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doaj-459f4fc0721b4519b1ab2568328f9b332020-11-25T02:00:14ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2010-01-0154223227Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive KeratectomyMohammad Ghoreishi,Hossein AttarzadehMehdi TavakoliHeidar Ali MoiniAlireza ZandiAmin MasjediAkram RismanchianPurpose: To compare the outcomes and complications of alcohol-assisted versus mechanical corneal epithelial debridement for photorefractive keratectomy (PRK). Methods: This randomized controlled trial included 1,250 eyes of 625 patients undergoing PRK for correction of myopia and myopic astigmatism. Each patient was randomly assigned to alcohol-assisted or mechanical epithelial removal. Results: A total of 658 eyes underwent alcohol-assisted epithelial removal while the epithelium was removed mechanically in 592 eyes. Mean spherical equivalent was ‑4.37}2.3 D in the alcohol group and ‑3.8}1.3 D in the mechanical group (P = 0.78). There was no significant difference in postoperative pain between the study groups (P = 0.22). Uncorrected visual acuity ≥ 20/20 and ≥ 20/40 was achieved in 90.9% versus 93.4% (P = 0.08), and 98.9% versus 99.5% (P = 0.36) of eyes in the alcohol and mechanical groups, respectively. Final refractive error within 1D of emmetropia was achieved in 90% versus 92.2% of eyes in the alcohol and mechanical groups, respectively (P = 0.23). Alcohol-assisted debridement required less time than mechanical debridement (96±18 vs. 118±26 seconds, P=0.035). There was no significant difference between the two groups in terms of early and late postoperative complications. Conclusion: Alcohol-assisted and mechanical epithelium removal are comparable in terms of efficacy and side effects. The method of epithelial debridement in PRK may be left to the surgeon′s choice.http://www.jovr.org/article.asp?issn=2008-322X;year=2010;volume=5;issue=4;spage=223;epage=227;aulast=Ghoreishi,Photorefractive Keratectomy; LasersExcimer; Epithelial Debridement; Ethanol |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohammad Ghoreishi, Hossein Attarzadeh Mehdi Tavakoli Heidar Ali Moini Alireza Zandi Amin Masjedi Akram Rismanchian |
spellingShingle |
Mohammad Ghoreishi, Hossein Attarzadeh Mehdi Tavakoli Heidar Ali Moini Alireza Zandi Amin Masjedi Akram Rismanchian Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy Journal of Ophthalmic & Vision Research Photorefractive Keratectomy; Lasers Excimer; Epithelial Debridement; Ethanol |
author_facet |
Mohammad Ghoreishi, Hossein Attarzadeh Mehdi Tavakoli Heidar Ali Moini Alireza Zandi Amin Masjedi Akram Rismanchian |
author_sort |
Mohammad Ghoreishi, |
title |
Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy |
title_short |
Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy |
title_full |
Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy |
title_fullStr |
Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy |
title_full_unstemmed |
Alcohol-assisted versus Mechanical Epithelium Removal in Photorefractive Keratectomy |
title_sort |
alcohol-assisted versus mechanical epithelium removal in photorefractive keratectomy |
publisher |
Knowledge E |
series |
Journal of Ophthalmic & Vision Research |
issn |
2008-322X |
publishDate |
2010-01-01 |
description |
Purpose: To compare the outcomes and complications of alcohol-assisted versus mechanical corneal epithelial debridement for photorefractive keratectomy (PRK).
Methods: This randomized controlled trial included 1,250 eyes of 625 patients undergoing PRK for correction of myopia and myopic astigmatism. Each patient was randomly assigned to alcohol-assisted or mechanical epithelial removal.
Results: A total of 658 eyes underwent alcohol-assisted epithelial removal while the epithelium was removed mechanically in 592 eyes. Mean spherical equivalent was ‑4.37}2.3 D in the alcohol group and ‑3.8}1.3 D in the mechanical group (P = 0.78). There was no significant difference in postoperative pain between the study groups (P = 0.22). Uncorrected visual acuity ≥ 20/20 and ≥ 20/40 was achieved in 90.9% versus 93.4% (P = 0.08), and 98.9% versus 99.5% (P = 0.36) of eyes in the alcohol and mechanical groups, respectively. Final refractive error within 1D of emmetropia was achieved in 90% versus 92.2% of eyes in the alcohol and mechanical groups, respectively (P = 0.23). Alcohol-assisted debridement required less time than mechanical debridement (96±18 vs. 118±26 seconds, P=0.035). There was no significant difference between the two groups in terms of early and late postoperative complications.
Conclusion: Alcohol-assisted and mechanical epithelium removal are comparable in terms of efficacy and side effects. The method of epithelial debridement in PRK may be left to the surgeon′s choice. |
topic |
Photorefractive Keratectomy; Lasers Excimer; Epithelial Debridement; Ethanol |
url |
http://www.jovr.org/article.asp?issn=2008-322X;year=2010;volume=5;issue=4;spage=223;epage=227;aulast=Ghoreishi, |
work_keys_str_mv |
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